Kolonoskopide Kalite Standartlarına Uyum ve İnkomplet Kolonoskopi Nedenleri: Prospektif Gözlemsel Çalışma
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P: 25-32
Mart 2019

Kolonoskopide Kalite Standartlarına Uyum ve İnkomplet Kolonoskopi Nedenleri: Prospektif Gözlemsel Çalışma

Turk J Colorectal Dis 2019;29(1):25-32
1. University of Health Sciences, Elazığ Training and Research Hospital, Clinic of Gastroenterological Surgery, Elazığ, Turkey
2. University of Health Sciences, Gaziyaşargil Training and Research Hospital, Clinic of Gastroenterological Surgery, Diyarbakır, Turkey
3. University of Health Sciences, Balıkesir Training and Research Hospital, Clinic of Gastroenterological Surgery, Balıkesir, Turkey
4. Şanlıurfa Training and Research Hospital, Clinic of Gastroenterological Surgery, Şanlıurfa, Turkey
5. University of Health Sciences, Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital, Clinic of Gastroenterologcal Surgery, İstanbul, Turkey
6. University of Health Sciences, Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital, Clinic of Gastroenterology, İstanbul, Turkey
Bilgi mevcut değil.
Bilgi mevcut değil
Alındığı Tarih: 13.08.2018
Kabul Tarihi: 12.09.2018
Yayın Tarihi: 26.03.2019
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Amaç:

Kolorektal patolojilerin tanısında kolonoskopi altın standarttır ve klinik uygulamalarda sık yapılan bir işlemdir. Bu çalışmada inkomplet kolonoskopi oranı, kolonoskopinin tamamlanmamasına etki eden faktörler ve kliniğimizin kolonoskopi kalite standartlarına uygunluğunun değerlendirilmesi amaçlanmıştır.

Yöntem:

Çalışma Ocak 2017-Aralık 2017 tarihleri arasında üçüncü basamak sağlık merkezinde prospektif olarak yapıldı. Kolonoskopi yapılan bireylerin demografik özellikleri, kolon temizlik durumu, inkomplet kolonoskopi nedenleri ve inkomplet kolonoskopiye etki eden faktörler incelendi. Kolonoskopisi tamamlanan ve tamamlanmayan popülasyon karşılaştırıldı.

Bulgular:

Toplam 756 kişi çalışmaya alındı. Yaş ortalaması 54±12,74 yıl olup %63’ü kadındı. Üç yüz kırk yedisinde (%45,9) komorbidite mevcuttu. Popülasyonun vücut kitle endeksi (VKİ) ortalaması 28,32±4,84 olup, 309’unda (%40,9) geçirilmiş batın cerrahi öyküsü vardı. Çekum entübasyon süresi 355±187 saniye olup 89 kişide (%11) kolonoskopi tamamlanamadı. İleri yaş (p=0,036), kadın cinsiyet (p=0,036), yüksek VKİ değeri (p=0,042), komorbidite varlığı (p=0,004), antiagregan/antikoagülan kullanımı (p=0,001), yetersiz barsak temizliği (p=<0,001) inkomplet kolonoskopi lehine anlamlı saptandı. Uygun barsak hazırlığı yapılamayan ve işlem tekrarı önerilen 46 (%6,1) vaka dışlandığında %93,9’unda (667/710) kolonoskopi tamamlanmıştır. Kötü barsak hazırlığı inkomplet kolonoskopinin en sık nedeni olup (%51,6), erkek cinsiyet (p=0,047) ve antiagregan-antikoagülan kullanımın (p=0,021) kolon temizliğine etki eden faktörler olarak belirlenmiştir. Kolonoskopisi tamamlanan grupta polip saptanma oranı %24,7 (165/ 667) olup güncel önerilen polip saptanma oranının altında kalmıştır.

Sonuç:

Uygun olmayan barsak temizliği, ileri yaş, kadın cinsiyet, artan VKİ, komorbidite ve antiagregan/antikoagülan kullanımı inkomplet kolonoskopiye etki eden faktörlerdir. Uygun olmayan barsak temizliğinin ana nedeni olduğu yüksek inkomplet kolonoskopi oranı ve düşük polip saptama oranı nedeniyle kolonoskopi kalite standartlarının altında kaldığımız görülmektedir.

Anahtar Kelimeler:
nkomplet kolonoskopi, barsak hazırlığı, kolonoskopide kalite

Kaynaklar

1
Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global patterns and trends in colorectal cancer incidence and mortality. Gut 2017;66:683-691.
2
Brenner H, Chang-Claude J, Jansen L, Knebel P, Stock C, Hoffmeister M. Reduced risk of colorectal cancer up to 10 years after screening, surveillance, or diagnosticcolonoscopy. Gastroenterology 2014;146:709-717.
3
Pan J, Xin L, Ma YF, Hu LH, Li ZS. Colonoscopy Reduces Colorectal Cancer Incidence and Mortality in Patients With Non-Malignant Findings: A Meta-Analysis. Am J Gastroenterol 2016;111:355-365.
4
Rex DK, Schoenfeld PS, Cohen J, Quality indicators for colonoscopy. Am J Gastroenterol 2015;110:72-90.
5
Johnson DA, Barkun AN, Cohen LB, Dominitz JA, Kaltenbach T, Martel M, Robertson DJ, Boland CR, Giardello FM, Lieberman DA, Levin TR, Rex DK, US Multi-Society Task Force on Colorectal Cancer. Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the US Multi-Society TaskForce on Colorectal Cancer. Gastroenterology 2014;147:903-924.
6
Bowles CJ, Leicester R, Romaya C, Swarbrick E, Williams CB, Epstein O. Aprospective study of colonoscopy practice in the UK today: are we adequately preparedfor national colorectal cancer screening tomorrow? Gut 2004;53:277-283.
7
Marshall JB, Barthel JS. The frequency of total colonoscopy and terminal ilealintubation in the 1990s. Gastrointest Endosc 1993;39:518-520.
8
Franco DL, Leighton JA, Gurudu SR. Approach to Incomplete Colonoscopy: New Techniques and Technologies. Gastroenterol Hepatol (NY). 2017;13:476-483.
9
Koido S, Ohkusa T, Nakae K, Yokoyama T, Shibuya T, Sakamoto N, Uchiyama K, Arakawa H, Osada T, Nagahara A, Watanabe S, Tajiri H. Factors associated with incomplete colonoscopy at a Japanese academic hospital. World J Gastroenterol 2014;20:6961-6967.
10
Liang CM, Chiu YC, Wu KL, Tam W, Tai WC, Hu ML, Chou YP, Chiu KW, Chuah SK. Impact factors for difficult cecal intubation during colonoscopy. Surg Laparosc Endosc Percutan Tech 2012;22:443-446.
11
Brahmania M, Park J, Svarta S, Tong J, Kwok R, Enns R. Incomplete colonoscopy: maximizing completion rates of gastroenterologists. Can J Gastroenterol 2012;26:589-592.
12
Shah HA, Paszat LF, Saskin R, Stukel TA, Rabeneck L. Factors associated with incomplete colonoscopy: a population-based study. Gastroenterology 2007;132:2297-2303.
13
Bernstein C, Thorn M, Monsees K, Spell R, O’Connor JB.   A prospective study of factors that determine cecal intubation time at colonoscopy. Gastrointest Endosc 2005;61:72-75.
14
Jaruvongvanich V, Sempokuya T, Laoveeravat P, Ungprasert P. Risk factors associated with longer cecal intubation time: a systematic review and meta-analysis. Int J Colorectal Dis 2018;33:359-365.
15
Lai EJ, Calderwood AH, DorosG, Fix OK, Jacobson BC. The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research. Gastrointest Endosc 2009;69:620-625.
16
Rutherfor CC, Calderwoo AH. Update on Bowel Preparation for Colonoscopy. Curr Treat Options Gastroenterol 2018;16:165-181.
17
Parra-Blanco A, Ruiz A, Alvarez-Lobos M, Amorós A, Gana JC, Ibáñez P, et al. Achieving the best bowel preparation for colonoscopy. World J Gastroenterol 2014;20:17709-17726.
18
Hassan C, Fuccio L, Bruno M, Pagano N, Spada C, Carrara S, Giordanino C, Rondonotti E, Curcio G, Dulbecco P, Fabbri C, Della Casa D, Maiero S, Simone A, Iacopini F, Feliciangeli G, Manes G, Rinaldi A, Zullo A, Rogai F, Repici A. A predictive model identifies patients most likely to have inadequate bowel preparation for colonoscopy.Clin Gastroenterol Hepatol 2012;10:501-506.
19
Villa NA, Pannala R, Pasha SF, Leighton JA. Alternatives to Incomplete Colonoscopy. Curr Gastroenterol Rep 2015;17:43.
20
Hanson ME, Pickhardt PJ, Kim DH, Pfau PR. Anatomic factors predictive of incomplete colonoscopy based on findings at CT colonography. AJR Am J Roentgenol 2007;189:774-779.
21
ASGE Standards of Practice Committee, Saltzman JR, Cash BD, Pasha SF, Early DS, Muthusamy VR, Khashab MA, Chathadi KV, Fanelli RD, Chandrasekhara V, Lightdale JR, Fonkalsrud L, Shergill AK, Hwang JH, Decker GA, Jue TL, Sharaf R, Fisher DA, Evans JA, Foley K, Shaukat A, Eloubeidi MA, Faulx AL, Wang A, Acosta RD.Bowel preparation before colonoscopy. Gastrointest Endosc 2015;81:781-794.
22
Jawa H, Mosli M, Alsamadani W, Saeed S, Alodaini R, Aljahdli E, Bazarah S, Qari Y. Predictors of inadequate bowel preparation for inpatient colonoscopy. Turk J Gastroenterol 2017;28:460-464.
23
Hendry PO, Jenkins JT, Diament RH. The impact of poor bowel preparation on colonoscopy: a prospective single centre study of 10,571 colonoscopies. Colorectal Dis 2007;9:745-748.
24
Standards of Practice Committee, Lichtenstein DR, Jagannath S, Baron TH, Anderson MA, Banerjee S, Dominitz JA, Fanelli RD, Gan SI, Harrison ME, Ikenberry SO, Shen B, Stewart L, Khan K, Vargo JJ. Sedation and anesthesia in GI endoscopy. Gastrointest Endosc 2008;68:205-216.
25
Rex DK, Chen SC, Overhiser AJ. Colonoscopy technique in consecutive patients referred for prior incomplete colonoscopy. Clin Gastroenterol Hepatol 2007;5:879-883.
26
Spada C, Hassan C, Barbaro B, Iafrate F, Cesaro P, Petruzziello L, Minelli Grazioli L, Senore C, Brizi G, Costamagna I, Alvaro G, Iannitti M, Salsano M, Ciolina M, Laghi A, Bonomo L, Costamagna G. Colon capsule versus CT colonography in patients with incomplete colonoscopy: a prospective, comparative trial. Gut 2015;64:272-281.
27
Chen Y, Duan YT, Xie Q, Qin XP, Chen B, Xia L, Zhou Y, Li NN, Wu XT. Magnetic endoscopic imaging vs standard colonoscopy: meta-analysis of randomized controlled trials. World J Gastroenterol 2013;19:7197-7204.
28
Hotta K, Katsuki S, Ohata K, Abe T, Endo M, Shimatani M, Nagaya T, Kusaka T, Matsuda T, Uraoka T, Yamaguchi Y, Murakami Y, Saito Y. A multicenter, prospective trial of total colonoscopy using a short double-balloon endoscope in patients with previous incomplete colonoscopy. Gastrointest Endosc 2012;75:813-818.
29
Yamada A, Watabe H, Takano N, Togo G, Yamaji Y, Yoshida H, Kawabe T, Omata M, Koike K. Utility of single and double balloon endoscopy in patients with difficult colonoscopy: a randomized controlled trial. World J Gastroenterol 2013;19:4732-4736.
30
Spada C, Pasha SF, Gross SA, Leighton JA, Schnoll-Sussman F, Correale L, González Suárez B, Costamagna G, Hassan C. Accuracy of first- and second-generation colon capsules in endoscopic detection of colorectal polyps: a systematic review and meta-analysis. Clin Gastroenterol Hepatol 2016;14:1533-1543.
31
Kaminski MF, Regula J , Kraszewska E, Polkowski M, Wojciechowska U, Didkowska J, Zwierko M, Rupinski M, Nowacki MP, Butruk E. Quality indicators for colonoscopyand the risk of interval cancer. N Engl J Med 2010;362:1795-1803.
32
Kaminski MF, Wieszczy P, Rupinski M, Wojciechowska U, Didkowska J, Kraszewska E, Kobiela J, Franczyk R, Rupinska M, Kocot B, Chaber-Ciopinska A, Pachlewski J, Polkowski M, Regula J. Increased rate of adenoma detection associates with reduced risk of colorectal cancer and death. Gastroenterology 2017;153:98-105.
33
Aday U, Gundes E, Ciyiltepe H, Cetin DA, Deger KC, Gulmez S, Senger AS, Bozdag E. Does antiaggregant administration lead to early diagnosis in proximal colon cancer? North Clin Istanb 2017;4:173-179.
34
von Renteln D, Robertson DJ, Bensen S, Pohl H. Prolonged cecal insertion time is associated with decreased adenoma detection. Gastrointest Endosc 2017;85:574-580.
35
Barclay RL, Vicari JJ, Doughty AS, Johanson JF, Greenlaw RL. Colonoscopic withdrawal times and adenoma detection during screening colonoscopy. N Engl J Med 2006;355:2533-2541.