ABSTRACT

Diffuse large B cell lymphoma is a type of Non-Hodgkin Lymphoma (NHL) presenting with an aggressive course. NHL involvement usually occurs on the upper parts of gastrointestinal system (GIS) where lymphatic tissue is found intensively. However the settlement of primary lesion in colon is rare.

The patient was sixty-seven years old male whose major complaints were abdominal colic pain due to partial intestinal obstruction. He underwent a right hemicolectomy after the tumor was confirmed by abdominal ultrasonography and computerized tomography.

Hereby the pathophysiology, diagnosis and the treatment of the disease is discussed on the unexpected survival of surgical treatment alone. Related to its rarity, due to the lack of randomized controlled trials, there is not a clear treatment algorithm for these cases. Reports on this subject in the literature are poor and limited to case reports or brief series. However, surgery is still the main treatment option with combined therapies.