ABSTRACT
Infections, inflammatory diseases and malignancies are the leading cause of Fever of Unknown Origin (FUO). Lymphoma, sarcoma, hepatic, cerebral and renal cancers are the most frequent malignancies causing FUO. Colorectal cancers rarely reported as the cause of FUO. We present a 70 year-old male patient who had presented with mild microsyter anemia and six months persistant fever. Colonoscopy was performed because of three positive repeats of Standart Fecal Occult Blood Test (FOBT), and colon cancer was diagnosed. Fever was recovered at postoperative period and there have been no recurrences and no fever for five years. Haematological and solid malignancies must be remembered at patients presenting with FUO. It must be considered that colon cancers have an higher incidance at geriatric patients, especially whom having iron deficiency microcyter anemia, and FOBT must have repeated three times as screening test.