Precocious Brain Metastasis of Colorectal Cancer: A Report of Two Cases

Kaymak, �ahin; Han�erlio�ullar�, O�uz; �nce, Mehmet; Sinan, H�seyin; Demirba�, Sezai

ISSN 2536-4898
E-ISSN 2536-4901

Volume: 28 Issue: 2 (2018)

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Precocious Brain Metastasis of Colorectal Cancer: A Report of Two Cases [Turk J Colorectal Dis ]

Turk J Colorectal Dis . 2017; 27(1): 34-37 | DOI: 10.4274/tjcd.80106

Precocious Brain Metastasis of Colorectal Cancer: A Report of Two Cases

�ahin Kaymak, O�uz Han�erlio�ullar�, Mehmet �nce, H�seyin Sinan, Sezai Demirba�
G�lhane Training and Research Hospital, Clinic of General Surgery, Ankara, Turkey

Colorectal cancer is one of the most common causes of death due to cancer. In the majority of patients, diagnosis of brain metastasis (80%) follows diagnosis of the systemic cancer (metachronous presentation). However, brain metastases can be diagnosed before primary tumour diagnosis (precocious presentation) or simultaneously (synchronous presentation). With this case report, we aim to share the experience we gained with these two cases of precocious brain metastasis. These cases demonstrate that tumour biology is one of the most important of the widely recognized prognostic factors of colorectal cancer.

Keywords: Colorectal, precocious brain metastasis, cancer

Precocious Beyin Metastaz� Olan Kolorektal Kanserli �ki Olgunun Sunumu

�ahin Kaymak, O�uz Han�erlio�ullar�, Mehmet �nce, H�seyin Sinan, Sezai Demirba�
G�lhane E�itim ve Ara�t�rma Hastanesi, Genel Cerrahi Klini�i, Ankara, T�rkiye

Kolorektal kanserler halen en �nemli kanser �l�m nedenlerinden biridir. Beyin metastazl� hastalar�n �o�unda (%80) metastaz sistemik kanserin tan�s� konulduktan sonra (metakron prezentasyon) ortaya ��kar. Ancak, baz� hastalarda beyin metastaz� primer t�m�r saptanmadan �nce (precocious prezentasyon) ya da ayn� zamanda (senkronize prezentasyon) te�his edilebilir. Biz de bu olgu sunumumuzda precocious beyin metastaz� ile ba�vuran iki olgumuzda kazanm�� oldu�umuz deneyimi payla�may� ama�lad�k. Bu iki olgudaki deneyimimiz, kolorektal kanserlerin yayg�n olarak kabul edilen prognostik fakt�rleri aras�nda, t�m�r biyolojisinin �nemli fakt�rlerden birisi oldu�udur.

Anahtar Kelimeler: Kolorektal, precocious beyin metastaz�, kanser

�ahin Kaymak, O�uz Han�erlio�ullar�, Mehmet �nce, H�seyin Sinan, Sezai Demirba�. Precocious Brain Metastasis of Colorectal Cancer: A Report of Two Cases. Turk J Colorectal Dis . 2017; 27(1): 34-37

Corresponding Author: �ahin Kaymak, T�rkiye

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