Lipoma of the colon is a rare benign non-epithelial tumor of the gastrointestinal tract. Usually asymptomatic, but larger ones can cause abdominal pain, diarrhea, constipation, bleeding and intussusception and, they can detect by colonoscopy, double contrast barium colonography and computed tomography. Lipomas of the colon smaller than 2 cm by endoscopy, while those larger than 2 cm by laparotomy or laparoscopic approach can be taken out. Our case was a 38-year-old female patient having chronic cramping abdominal pain and anemia which had not improved with treatment, in whose the descending colon there was a giant lipoma causing invagination. Lipoma were detected by colonoscopy and the histological examination was diagnosed as submucosal lipoma and then were operated in elective conditions. Colon lipomas, despite rare existence, should be kept in mind in the differential diagnosis of abdominal pathologies.
Keywords: Colon, lipoma, invagination, colonoscopy